Unsupervised 2D gel electrophoresis image segmentation based on active contours
نویسندگان
چکیده
منابع مشابه
Unsupervised 2D gel electrophoresis image segmentation based on active contours
This work introduces a novel active contour-based scheme for unsupervised segmentation of protein spots in two-dimensional gel electrophoresis (2D-GE) images. The proposed segmentation scheme is the first to exploit the attractive properties of the active contour formulation in order to cope with crucial issues in 2D-GE image analysis, including the presence of noise, streaks, multiplets and fa...
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Introduction Two-Dimensional Gel Electrophoresis technique is a convenient and well-established method to separate thousands of proteins on polyacrylamide gels, according to the differences in their net charge and their molecular mass [1]. Its digital output is an image which depicts proteins as bright or dark spots over a noisy and inhomogeneous background. Each protein is characterized by its...
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ژورنال
عنوان ژورنال: Pattern Recognition
سال: 2012
ISSN: 0031-3203
DOI: 10.1016/j.patcog.2011.08.003